I have replaced any bulbs I can with CF's. Over time, I've gotten used to the warm up time and buzzing. I have only two beefs at this point:

Using them in the laundry room causes me to miss stains that show up in natural and incandescent light. I have to carry an item to the window or to an incandescent that hasn't burned out yet...

The outdoor floods don't last more than a few days in my light sensor socket adaptor. I've had to go back to incandescent for those fixtures.

The only other problem is fit - sometimes they don't fit in an overhead fixture.

My solid waste agency is good about disposal options - the only pain is having to collect them separately from other trash.