We are building a new house and I would like to maximize my insulation in the walls R19 or so.We are in a tidal section of South East Va where it is humid and hot.

Is there any research or information on fumes caused by closed cell foam insulation?
Is there a risk of "sick house" due to inadequate flow of fresh air or fumes from the foam?

Will open cell foam gather too much humidity and leave an organic base for mold and such to grow?